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(1992) found that after 1965 the median ratio was one of 3:1 with patients beingmore violent than non-patients. Expands extracellular fluid volume (becauseit does not enter cells, mannitol draws waterfrom the intracellular compartment)—increases g.f.r. In the case of a categorical independent variable, the experimentermay select two of the many categories of the independent variable that are available. Given the availability of medications thattarget different pathologic processes, combination therapy isan attractive theoretical option

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